Nelson is from Cape Coast but was born in Accra on the 12th of November, 1985.
She had her basic and junior high education at St. Martin De Porres School in Accra and later went to Aggrey Memorial Senior High School. She had her tertiary education at Central University College, where she did a degree course in Human Resource Management.
In the Miss Ghana 2005 Beauty Pageant, she won the Best Talent award by performing an original rap song.
Her first lead role was the title character in the movie Princess Tyra. She shot about five more movies and then went to Nigeria to shoot her first collaboration with Genevieve Nnaji in 2007, which launched her career in Nollywood. Since then, she has filmed close to a hundred movies in Nigeria, Ghana, and Ivory Coast.